Mr. Mark Jaskowski

Mr. Mark Jaskowski

Chemist

mark.jaskowski@westpoint.edu

Biography


Mark Jaskowski is a Chemist in the Department of Chemistry and Life Sciences where he manages various laboratories and equipment in support of the educational and research initiatives in the chemistry program.  Mark has worked in a variety of positions in the pharmaceutical and biotech industries over the years including positions with Wyeth (Pfizer) and Merck.  He has published research from Princeton and Rutgers Universities.

Publications & Presentations


Peer-Reviewed Publications

A simple synthesis and evaluation of the bicyclo[8.3.0] enediyne framework. Tetrahedron Letters Volume 43, Issue 28, 8 July 2002, Pages 4947-4950. M.F. Semmelhack*, Mark Jaskowski, Richmond Sarpong, Douglas M. Ho.

Discovery of MRSA active antibiotics using primary sequence from the human microbiome Nat Chem Biol. 2016 Dec;12(12):1004-1006.  John Chu, Xavier Vila-Farres, Daigo Inoyama, Melinda Ternei, Louis J Cohen, Emma A Gordon, Boojala Vijay B Reddy, Zachary Charlop-Powers, Henry AZebroski, Ricardo Gallardo-Macias, Mark Jaskowski, Shruthi Satish, Steven Park, David S Perlin, Joel S Freundlich & Sean F Brady*

Human microbiome inspired antibiotics with improved β-lactam synergy against MDR Staphylococcus aureus. ACS Infect. Dis., 2018, 4 (1), pp 33–38 John  Chu, Xavier  Vila-Farres, Daigo  Inoyama, Ricardo  Gallardo-Macias, Mark Jaskowski, Shruthi  Satish, Joel  S.  Freundlich, and  Sean  F.  Brady*.

Optimization of N-benzyl-5-nitrofuran-2-carboxamide as an antitubercular agent. Bioorganic & Medicinal Chemistry Letters Volume 29, Issue 4, 15 February 2019, Pages 601-606. Ricardo Gallardo-Macias, Pradeep Kumar, Mark Jaskowski, Todd Richmann, Riju Shrestha, Riccardo Russo, Eric Singleton, Matthew D. Zimmerman, Hsin Pin Hoc, Veronique Dartois, Nancy Connell, David Alland, Joel S. Freundlich*.

Small Molecule Benzothiophene with In Vivo Efficacy in a Mouse Model of Drug-Resistant Enterococcus faecium InfectionSmall Molecule Benzothiophene with In Vivo Efficacy in a Mouse Model of Drug-Resistant Enterococcus faecium Infection. J. Med. Chem. 2024 67 (2), 1384-1392 Jan 15, 2024. Ricardo Gallardo-Macias, Riccardo Russo, Matthew Sherwood, Mark Jaskowski, Wissam Nasser, Pankaj Sharma, Margareta Tuckman, Eric Singleton, Hsin Pin Ho, Steven Park, Jimmy S. Patel, Amir George, David Perlin, Matthew D. Zimmerman, Nancy Connell, and Joel S. Freundlich*.

Inhibitors of Bacterial RNA Polymerase: Arylpropenoyl,and Arylcyclopropanecarboxyl Phloroglucinols. US Patent 10,450,292 B2. Filed Dec. 9 2016, and Issued Oct. 22, 2019. · Oct 22, 2019US Patent 10,450,292 B2. Filed Dec. 9 2016, and Issued Oct. 22, 2019. Richard H. Ebright*, Joel Freundlich, Nisha Mittal, Mark Jaskowski, Juan Shen, New Brunswick, NJ (US).


*Corresponding author