
Dr. Melanie E. Jones
Department Head
USMAPS Department of Natural Sciences
Dr. Melanie Jones is the Head of the Department of Natural Sciences at the United States Military Academy Preparatory School, West Point, New York. Dr. Jones received her PhD from New York Medical College in Microbiology and Immunology. Her primary research focused on the role of the androgen and androgen receptor in thyroid cancer. Prior to NY Medical College, she obtained a Bachelor of Science degree from Marist College and a concentration in Secondary Education. At Marist, she did research on bacteria that were able to breakdown Polycyclic Aromatic Hydrocarbons (PAHs), toxic chemicals in oil and gasoline. She also obtained her Master of Arts in Biology from SUNY New Paltz where she studied cytoskeleton formation in immune cells within modeled microgravity.
Dr. Jones began her teaching career as a teaching assistant for multiple undergraduate science courses. Upon graduating from Marist College, she began teaching full time in high school and middle school biology and physical science. After transitioning to her PhD program, she continued to teach or assist in multiple graduate courses at Touro University and NY Medical College. In 2014 she was hired at the United States Military Academy Preparatory School to develop a science program for cadet candidates. After serving as an instructor within the department and the acting department head, she was promoted to the Head of the Department of Natural Sciences in 2019. Dr. Jones is originally from this area of the Hudson Valley and enjoys the full range of seasonal sports in NY including hiking, swimming, and skiing. While at USMAPS she has served as the head swim instructor, a sponsor for the Corbin Forum—a club that facilitates mentoring and networking for female CCs , and an assistant sponsor for Recharge—a club for Christian fellowship.
Department Head 938-1944
Ph.D. - New York Medical College
M.A. - State University of New York at New Paltz
B.S. - Marist College
Research Interests
Thyroid Cancer, Immunology, Cell Signaling
Current Research
Jones ME, O'Connell T, Zhao H, Darzynkiewicz Z, Gupta A, Buchsbaum J, Shin E, Iacob C, Suslina N, Moscatello A, Schantz S, Tiwari R, Geliebter J. Androgen receptor activation decreases proliferation in thyroid cancer cells. Journal of Cellular Biochemistry. 2021 April 20; 122(9):1113-1125
Selected Publications
Gupta, A.; Carnazza, M.; Jones, M.; Darzynkiewicz, Z.; Halicka, D.; O’Connell, T.; Zhao, H.; Dadafarin, S.; Shin, E.; Schwarcz, M.D.; Moscatello, A.; Tiwari, R.K.; Geliebter, J. Androgen Receptor Activation Induces Senescence in Thyroid Cancer Cells. Cancers 2023, 15, 2198. doi: 10.3390/cancers15082198
O'Connell, T., Dadafirin, S., Jones, M., Rodriguez, T., Gupta, A., Shin, E., Moscatello, A., Iacob, C., Islam, H., Tiwari, R.K., Gelibter, J. Androgen Activity Is Associated With PD-L1 Downregulation in Thyroid Cancer. Front Cell Dev Biol. 2021. doi:10.3389/fcell.2021.663130
Jones ME, O'Connell T, Zhao H, Darzynkiewicz Z, Gupta A, Buchsbaum J, Shin E, Iacob C, Suslina N, Moscatello A, Schantz S, Tiwari R, Geliebter J. Androgen receptor activation decreases proliferation in thyroid cancer cells. Journal of Cellular Biochemistry. 2021 April 20; 122(9):1113-1125
Pinto JT, Krasnikov BF, Alcutt S, Jones ME, Dorai T, Villar MT, Artigues A, Li J, Cooper AJL. Kynurenine Aminotransferase III and Glutamine Transaminase L are Identical Enzymes that have Cysteine S-Conjugate Beta-Lyase Activity and can Transaminate L-Selenomethionine. J Biol Chem. 2014 Sep 17.
Pinto JT, Lee JI, Sinha R, MacEwan ME, Cooper AJL. Chemopreventive mechanisms of α-keto acid metabolites of naturally occurring organoselenium compounds. Amino Acids. 2011 June; 41(1): 29–41.