LTC Victor Jaffett, PhD

Assistant Professor

Director - Chemistry Program

Chemistry & Life Science

Center for Molecular Science

victor.jaffett [at] westpoint.edu
Lieutenant Colonel Jaffett is an Academy Professor in the Department of Chemistry and Life Science. He earned a B.S. in systems engineering from the United States Military Academy in 2002, and commissioned as a signal officer. He has served in tactical signal, and Stryker infantry units with operational deployments to Iraq. He received both his MS and Ph.D. in Chemistry from the University of Wisconsin at Madison in 2011 and 2019 respectively. LTC Jaffett is currently the Course Director for Organic Chemistry I and II. Previously, he has taught General Chemistry I and II. Additionally, he formerly served as the Assistant Course Director for Organic Chemistry I and II.

Ph.D. in Chemistry - University of Wisconsin at Madison

 

M.S. in Chemistry - University of Wisconsin at Madison

 

B.S. in Systems Engineering - United States Military Academy

Current Research

Lieutenant Colonel Jaffett’s research interests include synthesis of Iridium cyclometalated complexes for exploration of non-linear optical properties and the characterization of thermal degradation products of polyfluoroalkyl substances.

Selected Publications

Ryan P. Kreiser, Aidan K. Wright, Liam R. Sasser, Dillon J. Rinauro, Tristan McKenzie, J. Alex Albright, Lance Richardson, Victor A. Jaffett, Dawn E. Riegner, Lam T. Nguyen, Kathleen LeForte, Michael Zasloff, Fabrizio Chiti, Jared E. Hollows, Michele Vendruscolo, Ryan Limbocker*. “A brain permeable aminosterol regulates cell membranes to mitigate the toxicity of diverse pore-forming agents.” ACS Chem. Neurosci. 2022, 13, 8, 1219–1231.

Victor A. Jaffett, Jhewelle Fitz-Henley, Muhammad Khalifa, Ilia Guzei, Jennifer Golden*. Diastereoselective, Multicomponent Synthesis of Pyrrolopyrazinoquinazolinones via a Tandem Quinazolinone Rearrangement/ Intramolecular Ring Closure of Tautomeric (Z)-Benzamidines. Org. Lett., 2021, 23, 5799–5803, DOI:10.1021/acs.orglett.1c01955.

Gang Yan, Bereket L. Zekarias, Xiaoyu Li, Victor A. Jaffett, Ilia A. Guzei, Jennifer E. Golden*. Divergent 2-Chloroquinazolin-4(3H)-one Rearrangement: Twisted-Cyclic Guanidine Formation or Ring-Fused N-Acylguanidines via a Domino Process. Chem. Eur. J., 2020, 26, 2486-2492.

Victor A. Jaffett, Alok Nerurkar, Xufeng Xao, Ilia Guzei, Jennifer Golden*. Telescoped synthesis of C3-functionalized (E)-arylamidines using Ugi–Mumm and regiospecific quinazolinone rearrangements. Org. Biomol. Chem., 2019,17, 3118-3128.

*Corresponding author